| Home | Score | Away | League | Time (CST) |
|---|---|---|---|---|
| Forward Madison | 4:0 | Richmond Kickers | American USL League One | 08:00 |
| Botafogo | — | Santos | Brazilian Serie A | 06:30 |
| Vitória | — | Vasco da Gama | Brazilian Serie A | 06:30 |
| Vålerenga | — | Aalesund | Norwegian Eliteserien | 01:00 |
| CF Montréal | — | Toronto FC | American Major League Soccer | 07:30 |
| NJ/NY Gotham | 1:0 | Washington Spirit | American NWSL | 08:00 |
| Afturelding | — | Leiknir Reykjavík | Icelandic 1 deild karla | 03:15 |
| Bunyodkor | — | Nasaf | Uzbekistan Super League | 23:00 |
| Neftchi Fergana | — | Buxoro | Uzbekistan Super League | 23:00 |
| Sogdiana Jizzakh | — | Xorazm Urganch | Uzbekistan Super League | 23:00 |
| Forge | — | Pacific | Canadian Premier League | 07:00 |
| Elva | — | Viimsi | Estonian Esiliiga | 00:00 |
| Aucas | — | Independiente del Valle | Ecuadorian Serie A | 05:30 |
| Barcelona SC | 1:1 | Guayaquil City | Ecuadorian Serie A | 08:30 |
| CRB | — | Náutico | Brazilian Serie B | 07:00 |
| Atlético FC | — | San Antonio FC | Ecuadorian Serie B | 03:00 |
| Cumbayá | — | 9 de Octubre | Ecuadorian Serie B | 00:00 |
| Ottawa Rapid | — | Halifax Tides | Canadian Northern Super League | 07:00 |
| Ekibastuz | — | Shakhter Karagandy | Kazakhstan First League | 20:00 |
| Taraz | — | Aktobe-2 | Kazakhstan First League | 20:00 |